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KMID : 0614620200750060356
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Korean Journal of Gastroenterology
2020 Volume.75 No. 6 p.356 ~ p.361
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Metachronous Development of Peritoneal Carcinomatosis in a Patient with Autoimmune Pancreatitis
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Lee Kyu-Won
Chang Jae-Hyuck
Kim Jean-A
Kim Tae-Ho
Kim Chang-Whan
Kim Jae-Kwang
Han Sok-Won
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Abstract
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Autoimmune pancreatitis (AIP) is a rare and unique type of chronic pancreatitis. The prognosis of AIP, particularly when associated with pancreatic cancer or a related malignancy, is not known. Only a few cases, where metachronous pancreas-related cancer developed during follow-up, have been reported. Most of these patients either underwent surgery or steroid therapy. This paper reports a case of a 66-year-old woman with untreated type I AIP who developed peritoneal carcinomatosis more than 2 years later. Initially, the patient had a markedly elevated serum IgG4 level and a diffuse, infiltrative mass-like lesion in the pancreatic head, in which the biopsy results were consistent with type I AIP. The patient was not treated with steroids because of a cerebellar infarction. Twenty-eight months after the diagnosis of AIP, peritoneal carcinomatosis developed without noticeable changes in the pancreas from the initial findings.
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KEYWORD
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Autoimmune pancreatitis, Immunoglobulin G4-related disease, Pancreatic neoplasms, Peritoneal neoplasms
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